ki:elements

pioneers in speech biomarkers

ki:elements

pioneers in speech biomarkers

ki:elements

pioneers in speech biomarkers

ki: künstliche intelligenz (German, artificial intelligence)

our mission = your unmet clinical needs

getting assets faster to orbit & exploring uncharted terrain

ki:elements pioneers speech-based assessments for neurological & psychiatric pathologies, modelling approved biomarkers.

We model symptoms

  • that are not measured remotely or at such high sampling rate
  • that today receive no objective signal of the same quality

Speech biomarkers convince through scalability, ecological validity, low patient burden.

our offering = your steps towards a successful mission

fueling neuroscience in four stages

consulting

research

development

commercialisation

our engine = your scientifically valid solution

Detecting symptoms through linguistic and paralinguistic (acoustic) processing of speech.

  • alzheimer's disease
  • multiple sclerosis
  • depression
  • parkinson's disease
Screening for AD biomarker noninvasively
Input:
Throughput:
Output:
connected speech from story retelling
syntactic complexity + semantic units/story keywords
language & episodic memory impairment markers
Differentiating between cognitive syndrome and fatigue.
 
Input:
Throughput:
Output:
verbal fluency recording (VF)
pitch & prosody + VF temporal & linguistic clustering
fatigue + dysexectuive syndrome markers
Disease course and relapse prognosis
Input:
Throughput:
Output:
free connected speech from speech diary entries
sentiment + keywords + acoustic microvariations,
pitch & prosody
suicide risk and relapse markers
Differentiating between motor speech problem and cognitive language problems
 
Input:
Throughput:
Output:
free connected speech
pitch & loudness variations + microvariations + syntactic complexity
tremor + language markers

our ai = your clinical research

launching truly into disciplinary missions

At ki: we believe in the value of interdisciplinary missions. Constantly pushing the limits at the juncture of applied artificial intelligence, natural language processing and neuroscience, interdisciplinary research is in our DNA. Why care?

  • transparency for improved compliance of your solutions
  • clinical explainability down to a symptom level
  • validity through solid research #rocketscience

our trajectory = your clinical value add

exploring a whole space of opportunities

screening

  • Screening for ADRD* biomarker noninvasively
  • Screening for affective disturbances as risk factors

diagnosis

  • Differential diagnosis to other dementia causes (e.g. FTLD)
  • Differential diagnosis to pseudo-dementia due to affective disorders

monitoring

  • Low-threshold monitoring of cognition and mood
  • Predicting conversion probability from MCI to AD through monitoring

screening

  • Hypomanic episodes in individuals at risk
  • Low-threshold screening for depressive symptoms

diagnosis

  • Differential diagnosis between unipolar depression and bipolar disorder
  • Characterization of cognitive symptoms in mania

monitoring

  • Stratification of different bipolar subforms by tracking of symptoms
  • Disease course and relapse prognosis

screening

Although, screening and early detection for MS is of high importance to avoid later impairments, we do not see early symptoms that can be measured through speech

diagnosis

  • Differentiating between cognitive syndrome and fatigue
  • Differentiating between impaired language (cognition) and impaired speech (dysarthria)

monitoring

  • Stratification of different MS subforms by tracking of symptoms
  • Prognosis of future episodes

screening

  • Negative symptom detection in prodromal phase within (ultra) high risk subjects

diagnosis

  • Objective classification of formal thought disorder

monitoring

  • Negative symptom monitoring during remission
  • Disease course and relapse prognosis
  • Monitoring of formal thought disorder

screening

  • Screening for cognitive symptoms as a precursor of motor symptoms

diagnosis

  • Differentiating between motor speech problem and cognitive language problems

monitoring

  • Managing progressive disease course by monitoring treatment response

    k

  • Predicting dementia risk
  • alzheimer's disease
  • affective disorders
  • multiple sclerosis
  • schizophrenia

  • parkinson's disease

screening

  • Screening dor ADRD biomarker noninvasively
  • Screening for affective disturbances as risk factors

diagnosis

  • Differential diagnosis to other dementia causes (e.g. FTLD)
  • Differential diagnosis to pseudo-dementia due to affective disorders

monitoring

  • Low-threshold monitoring of cognition and mood
  • Predicting conversion probability from MCI to AD trough monitoring

screening

  • Hypomanic eposides in individuals at risk
  • Low threshold screening for depressive symptoms

diagnosis

  • Differential diagnosis between unipolar depression and bipolar disorder
  • Characterization of cognitive symptoms in mania

monitoring

  • Stratification of different bipolar subforms by tracking of symptoms
  • Disease, course and relapse prognosis

screening

Although, screening and early detection for MS is of high importance to avoid later impairments, we do not see early symptoms that can be measured through speech

diagnosis

  • Differentiating between cognitive syndrome and fatigue
  • Differentiating between impaired language (cognition) and impaired speech (dysarthria)

monitoring

  • Stratification of different MS subforms by tracking of symptoms
  • Prognosis of future episodes

screening

  • Negative symptom detection in prodromal phase within (ultra) high risk subjects

diagnosis

  • Although, screening and early detection for MS is of high importance to avoid later impairments, we do not see early symptoms that can be measured through speech

monitoring

  • Negative symptom monitoring during remission

  • Disease course and relapse prognosis

  • Monitoring of formal thought disorder

screening

  • Screening for cognitive symptoms as a precursor of motor symptoms

diagnosis

  • Differentiating between motor speech problem and cognitive language problems

monitoring

  • Managing progressive disease course by monitoring treatment response

  • Predicting dementia risk

our crew = your onboarding opportunity

working together as a team

our mission control = your point of contact

getting things done

Am Holzbrunnen 1a
66121 Saarbrücken
Germany