ki:elements

Pioneers in speech biomarkers

Digital biomarkers for every pathology

Modelling symptoms that cannot be measured remotely or objectively today

Biomarkers measure indicators of normal biological processes, pathogenic processes, or responses to an exposure or intervention. If this biomarker is collected using a digital sensing product, it’s known as a digital biomarker. If this sensing product captures speech, we call it a speech biomarker.

ki:elements biomarkers are not specified to indications but measure symptoms across indications – one biomarker serves multiple pathologies.

Disease agnostic, low-burden & scalable

Speech biomarkers work remotely, automatically, and are low-burden

Speech biomarkers have the advantage of being fully functional in remote settings without the need of any specific hardware, technique or even invasive procedures making them highly scalable and very cost-effective. The probe of speech needed can be collected with very low burden for patients or study participants resulting in incomparable patient compliance — in pre-screening, as trial endpoint or in drug companion use cases.

ki:e speech biomarkers Blood biomarkers Imaging biomarkers Clinical (rating) scale
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Non-invasive
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Patient compliance
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Use case example: Pre-screening in AD

Enrollment as key barrier for AD trials

80%

of trials fail to meet enrolment timelines

30%

of clinical trial's timeline is spent on patient recruitment

$5.9B

spent annually on clinical trial recruitment

5%

or less of potential candidates enrolled in clinical trials

Using ki:e SB-C will significantly reduce the number of candidates invited to sites for screening and improve successful screen-in rate.

Biomarker example: validity of the ki:e SB-C biomarker

Under the hood of pre-screening — psychometric properties of ki:e SB-C

correlation with the MMSE

Strong correlation of the ki:e SB-C biomarker with MMSE total score.

discriminating between stages

Significant group differences between dementia, MCI and HC.

Better than the sum of it

Scientifically backed and co-developed with leading experts

ki:e speech biomarkers are built upon groundbreaking peer-reviewed scientific results across the fields of clinical neuropsychology, ageing neuroscience, machine learning and natural language processing.

>> more than 50 publications

>> involved in more than 30 studies

>> more than 5 years of research & experience

>> 8 active TAs

>> 2.7x YOY growth

>> 8 supported languages

The State Chancellery of Saarland supports ki:elements in the development of our research platform (Data Science Platform), which enables our data science staff to conduct better, faster, high-quality and secure research remotely.

The State Chancellery of Saarland supports ki:elements in the development of our research platform (Data Science Platform), which enables our data science staff to conduct better, faster, high-quality and secure research remotely.

The Prospect AD study which we are doing together with sites in Sweden, Germany, France and the UK is funded by the ADDF.

ki:elements is a Spin-off of the german research centre for Artificial Intelligence.

We are and have been involved in multiple projects funded by the BMBF.

With the Digital Hub Initiative (de:hub Initiative), the Federal Ministry for Economic Affairs and Climate Protection promotes digital innovations in Germany. As one of twelve de:hubs, the DIGITAL-HUB supports innovation in the field of digitalisation for chemistry and health through targeted funding. ki:elelements is a network partner of the DIGITAL-HUB.

The State Chancellery of Saarland supports ki:elements in the development of our research platform (Data Science Platform), which enables our data science staff to conduct better, faster, high-quality and secure research remotely.

The Prospect AD study which we are doing together with sites in Sweden, Germany, France and the UK is funded by the ADDF.

With the Digital Hub Initiative (de:hub Initiative), the Federal Ministry for Economic Affairs and Climate Protection promotes digital innovations in Germany. As one of twelve de:hubs, the DIGITAL-HUB supports innovation in the field of digitalisation for chemistry and health through targeted funding. ki:elelements is a network partner of the DIGITAL-HUB.

ki:elements is a Spin-off of the german research centre for Artificial Intelligence.

… as well as 2 of the 5 top pharma companies in the world and many university clinics all over Europe.

Shape the future of health

Inspire & get inspired

Excited to meet you and talk about your ideas, visions or possible collaboration – no matter if your background is in pharma, research or healthcare. Feel free to contact us directly via our LinkedIn profiles linked below.

Nicklas
Linz

CEO
data Scientist

Dr. Johannes
Tröger

CSO
Psychologist

Janna
Herrmann

CTO
Computer Scientist

Dr. Alexandra
König

Clinical Research
Coordinator

Dr. Duy
Truong

Computer Scientist

Jannic
Warken

Computer Scientist

Louisa
Schwed

data Scientist

Elisa
Mallick

data scientist

Dr. Jian
Zhao

Senior Regulatory &
Medical Affairs Manager

Mario
Mina

Data Scientist

Daniel
Kettering

System Engineer

John
Nonnenmacher

Signal Processing
Engineer

Simona
Schäfer

Clinical Researcher

Sol
Tovar

Research Assistant

Dr. Ebru
Baykara

Clinical Research
Manager

Susanne
Henne

team assistance

Baris
Kalem

Working student
quality management

Felix
Dörr

Working student
Data Science

Become a part of our team

Get in touch

& work with us

Reach out to us via LinkedIn in by clicking on our profiles above or write us an email using the contact form. We’re looking forward to working with you!

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